Oobli is the first commercially scaled company with FDA GRAS status as an ingredient and FEMA GRAS affirmed as a flavor.
Date last modified: May 2026
FDA GRAS “No Questions” Letter means that after reviewing our GRAS notice—including scientific data and safety assessments—the U.S. Food and Drug Administration stated it has no questions regarding our conclusion that the ingredient is safe under its intended conditions of use. This outcome confirms that FDA has no objections to the safety of our sweet proteins for their intended use.
Brazzein-53
Mar 11, 2024
General purpose sweetener replacement for foods and beverages
Confirming that brazzein-53, a sweet-tasting protein naturally occurring in the oubli fruit, is Generally Recognized as Safe (GRAS) for use as a sweetener in food and beverages
Brazzein-54
Sept 2, 2025
General purpose sweetener replacement for foods and beverages
Confirming that brazzein-54, a sweet-tasting protein naturally occurring in the oubli fruit, is Generally Recognized as Safe (GRAS) for use as a sweetener in food and beverages
Monellin
Nov 22, 2024
General purpose sweetener replacement for foods and beverages
Confirming that monellin, a sweet-tasting protein naturally occurring in the serendipity berry, is Generally Recognized as Safe (GRAS) for use as a sweetener in food and beverages
FEMA GRAS (Flavor and Extract Manufacturers Association) means that a panel of independent scientific experts has evaluated the ingredient and determined it is safe for use as a flavor ingredient under its intended conditions of use.
FEMA number: 5101
Oct 21, 2025
Use as a natural flavor in foods and beverages
Confirming that Oubli Fruit Sweet Protein, a sweet-tasting protein naturally occurring in the oubli fruit, is recognized as General Recognized as Safe (GRAS) for the use of the substance as a flavoring with modifying properties in select food categories and specified use levels.
FEMA number: 5101
Oct 21, 2025
Use as a natural flavor in foods and beverages
Confirming that Oubli Fruit Sweet Protein, a sweet-tasting protein naturally occurring in the oubli fruit, is recognized as General Recognized as Safe (GRAS) for the use of the substance as a flavoring with modifying properties in select food categories and specified use levels.
FEMA number: 5058
Mar 19, 2024
Use as a natural flavor in foods and beverages
Confirming that Katemfe Plant Sweet Protein, a sweet-tasting protein naturally occurring in the West African katemfe plant, is recognized as General Recognized as Safe (GRAS) for the use of the substance as a flavoring with modifying properties in select food categories and specified use levels.
FEMA number: 5110
Apr 29, 2026
Use as a natural flavor in foods and beverages
Confirming that monellin, a sweet-tasting protein naturally occurring in the serendipity berry, is recognized as General Recognized as Safe (GRAS) for the use of the substance as a flavoring with modifying properties in select food categories and specified use levels.
Ready to innovate?. Oobli sweet proteins are available for sampling today!
